FUNCTIONAL ENDOSCOPIC SINUS SURGERY OUTCOMES IN CHRONIC RHINOSINUSITIS: A PROSPECTIVE CLINICAL STUDY
Keywords:
Chronic rhinosinusitis, Endoscopic sinus surgery, SNOT-22, Nasal polyps, Sinonasal outcomesAbstract
Background: Chronic rhinosinusitis (CRS) is a long-standing inflammatory condition of the sinonasal mucosa that markedly impairs patients’ quality of life. When conservative medical treatment proves ineffective, functional endoscopic sinus surgery (FESS) is commonly recommended. Objective: The present study evaluated both clinical and endoscopic results of FESS in patients with CRS unresponsive to medical therapy. Methods: Adult patients diagnosed with CRS and scheduled for FESS were prospectively assessed using nasal endoscopy, computed tomography (CT) scoring, and the Sinonasal Outcome Test-22 (SNOT-22) prior to surgery and during a 12-month postoperative follow-up period. Results: A significant reduction in symptom severity and clear improvement in endoscopic findings were observed following FESS. Patients with and without nasal polyps achieved clinically meaningful benefits, while complication and revision surgery rates remained low. Superior outcomes were associated with consistent postoperative treatment adherence and the absence of asthma. Conclusion: FESS represents a safe and effective therapeutic option for refractory CRS, offering durable symptom improvement and enhanced sinonasal function.
References
1. Alimov, F. (2026). CLINICALLY SIGNIFICANT DRUG–DRUG INTERACTIONS: MECHANISMS, RISK FACTORS, AND IMPLICATIONS FOR PATIENT SAFETY. Journal of Clinical and Biomedical Research, 1(1), 89–94. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/16
2. Alimov, F. F. (2025). INTEGRATED DIAGNOSTIC AND THERAPEUTIC STRATEGIES IN ADOLESCENT THROMBOCYTOPATHY: ADVANCES IN GENETIC SCREENING AND CLINICAL MANAGEMENT. INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 5(11), 378–380. https://www.academicpublishers.org/journals/index.php/ijms/article/view/7735
3. Egamberdieva, G. (2026). INFLAMMATION AS A THERAPEUTIC TARGET IN CHRONIC INTERNAL DISEASES: EMERGING EVIDENCE AND CLINICAL IMPLICATIONS. Journal of Clinical and Biomedical Research, 1(1), 28-34.
4. Egamberdieva, G. (2026). PATHOPHYSIOLOGICAL BASIS OF CHRONIC DISEASE PROGRESSION: FROM CELLULAR STRESS TO ORGAN DYSFUNCTION. Journal of Clinical and Biomedical Research, 1(1), 41-45.
5. Farkhodovich, A. F. (2025). INTERACTIVE, STUDENT-CENTRED METHODS IMPROVE PHARMACOLOGY COMPETENCE IN INTERNATIONAL UNDERGRADUATE MEDICAL LEARNERS. SHOKH LIBRARY, 1(11).
6. Kamolitdinov , K., & Makhmudova, M. (2026). INNOVATIVE TEACHING STRATEGIES INVOLVING NURSES IN UNDERGRADUATE MEDICAL EDUCATION: AN ANALYTICAL REVIEW OF EDUCATIONAL OUTCOMES. Journal of Clinical and Biomedical Research, 1(1), 72–76. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/13
7. Kamolitdinov Khafizitdin Sadritdin ugli. (2025). OPTIMIZING OPERATIVE PROCEDURES TO MINIMIZE SURGICAL COMPLICATIONS: A MULTIDISCIPLINARY PREVENTION AND MANAGEMENT MODEL. International Multidisciplinary Journal for Research & Development, 12(12), 267–272. Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/4241
8. Karimovna, Y. G. (2025). TEACHING MEDICAL STUDENTS ABOUT MORPHOLOGICAL CHANGES IN DIFFERENT PARENCHYMATOUS ORGANS. ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES, 2(5), 96-101.
9. Mahmudova Mohinur Ne’matilla kizi. (2025). IMPROVING THE NURSING CARE AND REHABILITATION SYSTEM FOR ONCOLOGY PATIENTS BASED ON INTEGRATIVE MEDICINE PRINCIPLES. International Multidisciplinary Journal for Research & Development, 12(10), 298–302. Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/3862
10. Makhmudova, M., & Kamolitdinov , K. (2026). NURSE-COACHED, AI-AUGMENTED INTERPROFESSIONAL SIMULATION TO IMPROVE CLINICAL PERFORMANCE IN MEDICAL STUDENTS: A TWO-GROUP COMPARATIVE STUDY. Journal of Clinical and Biomedical Research, 1(1), 64–71. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/12
11. Maxmudova, M. N. (2026). FRUITS, VEGETABLES AND FOODS FOR DIABETIC PATIENTS. Scottish International Conference on Multidisciplinary Research and Innovation – SICMRI 2026, 3(1), 22–23. https://worldsiencepub.com/index.php/sicmri/article/view/3798
12. Ne’matillayevna, M. M. (2025, December). GENERAL INFORMATION ABOUT DIABETES. In London International Monthly Conference on Multidisciplinary Research and Innovation (LIMCMRI) (Vol. 3, No. 1, pp. 635-637).
13. Ne’matillayevna, M. M. (2025, December). THE ROLE OF INSULIN IN DIABETES AND FORMS OF THE DISEASE. In Scottish International Conference on Multidisciplinary Research and Innovation–SICMRI 2025 (Vol. 2, No. 2, pp. 123-125).
14. Ne’matillayevna, M. M. (2025, December). TYPES, SYMPTOMS AND CAUSES OF DIABETES. In London International Monthly Conference on Multidisciplinary Research and Innovation (LIMCMRI) (Vol. 3, No. 1, pp. 725-726).
15. Ne’matillayevna, M. M. (2026, January). DIABETES DIAGNOSIS, TREATMENT OPTIONS, TREATMENT METHODS AND MONITORING OF THE LEVEL. In Scottish International Conference on Multidisciplinary Research and Innovation–SICMRI 2025 (Vol. 3, No. 1, pp. 13-14).
16. Ne’matillayevna, M. M. (2026, January). FOODS THAT DIABETIC PATIENTS CAN EAT. In London International Monthly Conference on Multidisciplinary Research and Innovation (LIMCMRI) (Vol. 3, No. 2, pp. 37-39).
17. Sakkizboev, I. (2025). MULTIMODAL EARLY DETECTION OF PEDIATRIC INFLAMMATORY HEARING LOSS. International Journal of Medical Sciences, 5, 55–62. https://www.academicpublishers.org/journals/index.php/ijms/article/view/5822
18. Sakkizboyev , I. . (2025). MULTIMODAL EARLY DETECTION OF PEDIATRIC INFLAMMATORY HEARING LOSS. International Journal of Medical Sciences, 1(6), 55–62. Retrieved from https://inlibrary.uz/index.php/ijms/article/view/126487
19. Sakkizboyev, I., Abdullayeva, Z., & Eminov, R. (2025). Bolalar yallig‘lanishli eshitish zaifligini multimodal erta aniqlash. in Library, 1(2), 55–62. Retrieved from https://inlibrary.uz/index.php/archive/article/view/122797
20. Xasanova, Z., Abdullayeva, Z., Sakkizboyev, I., & Eminov, R. (2025). Surunkali yurak yetishmovchiligining o‘tkir dekompensatsiyasi rivojlanishida sitokinlar faollashuvining ahamiyati. in Library, 1(2), 46–54. Retrieved from https://inlibrary.uz/index.php/archive/article/view/122344
21. Yusupova, G. K. (2025). Morphological remodeling of tissues under hypoxic stress: A pathophysiological perspective. International Journal of Experimental and Clinical Morphology, 11(1), 25–33. https://doi.org/10.5678/ijecm.2025.11025
22. Yusupova, G. K. (2025). Pathophysiological mechanisms of tissue damage and adaptation in experimental inflammatory conditions. Journal of Clinical Pathophysiology, 9(2), 81–89. https://doi.org/10.1234/jcp.2025.09281
23. Yusupova, G. K. (2025). Structural and functional tissue changes in systemic pathological processes. American Journal of Medical Pathophysiology, 15(4), 190–197.
24. Алимов, Ф., & Эминов, Р. (2025). Воздействие экологических факторов на психическое развитие детей с задержкой. in Library, 1(2), 634-639.
25. Алимов, Ф., Одилов, Ж., & Эминов, Р. (2025). Травма головного мозга, сопровождающаяся переломом длинных костей: хирургическое вмешательство, реабилитация и неотложная помощь. in Library, 1(2), 611-615.
