BACTERIAL SKIN AND SOFT TISSUE INFECTIONS: ANTIBIOTIC RESISTANCE PATTERNS IN LOCAL CLINICAL PRACTICE
Keywords:
cutaneous infections, antibiotic resistance, bacterial pathogens, antimicrobial susceptibility, regional surveillance, clinical dermatologyAbstract
Bacterial skin and soft tissue infections (SSTIs) are a significant reason for outpatient consultations and antibiotic prescriptions globally. The increasing prevalence of antimicrobial resistance has challenged empirical treatment options, especially in regional clinical environments with little surveillance data. This study sought to examine bacterial causes and antibiotic resistance trends in individuals with SSTIs in local clinical settings. A retrospective observational study was performed at the Radeski Skin & Aesthetic Clinic in the Fergana Valley, Uzbekistan. Clinical specimens from patients with purulent and non-purulent skin and soft tissue infections were cultured, and antimicrobial susceptibility testing was conducted following normal laboratory techniques. The most often isolated pathogens comprised Staphylococcus aureus, Streptococcus pyogenes, and Gram-negative bacteria including Escherichia coli and Pseudomonas aeruginosa. Elevated resistance rates were detected for frequently administered antibiotics, such as penicillins and macrolides, although susceptibility remained generally intact for glycopeptides and some fluoroquinolones.
References
1. Alieva, Z., & Dadajonova, M. (2026). DIAGNOSIS AND MANAGEMENT OF PREMATURE OVARIAN INSUFFICIENCY. Journal of Clinical and Biomedical Research, 1(1), 1-7.
2. Bokijonovich, K. N. (2024). Enhancement of Exclusive Competencies of Foreign Students by Teaching the History of Medicine in Medical Education. World Bulletin of Social Sciences, 32, 41-44.
3. Bokijonovich, K. N. B. K. N. (2022). TURKISTON MUXTORIYATI BOSH VAZIRI O ‘RINBOSARI–ISLOM SHOAHMEDOV HAYOTI VA FAOLIYATINING YANGI QIRRALARI. Farg'ona davlat universiteti, (2), 18-18.
4. Dadajonova, A. (2025). ERTA TUXUMDON YETISHMOVCHILIGINI TASHXISLASHDA ULTRATOVUSH VA QON ZARDOBI BIOMARKERLARINING QIYOSIY ANIQLIK DARAJASI. In ILM FAN YANGILIKLARI KONFERENSIYASI. https://worldlyjournals.com/index.php/ztvdq/article/view/16785/20780
5. Dadajonova, M., & Alieva, Z. (2026). EARLY DIAGNOSIS OF OVARIAN INSUFFICIENCY AND APPROACHES. Journal of Clinical and Biomedical Research, 1(1).
6. DIGITAL TOOLS FOR REPRODUCTIVE HEALTH MANAGEMENT IN UZBEKISTAN (Dadajonova Mashhura Akhmadjon kizi, Alieva Zarnigor Valijon kizi, Trans.). (2025). London International Monthly Conference on Multidisciplinary Research and Innovation (LIMCMRI), 3(1), 548-552. https://worldsiencepub.com/index.php/lmc/article/view/2529
7. EARLY DIAGNOSIS OF OVARIAN INSUFFICIENCY METHODS. (2025). International Journal of Medical Sciences, 5(10), 481-489. https://doi.org/10.55640/
8. EARLY IDENTIFICATION OF OVARIAN FUNCTIONAL DECLINE AND CONTEMPORARY APPROACHES TO CLINICAL MANAGEMENT. (2025). ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES, 2(5), 83-87. https://innoworld.net/index.php/ojmns/article/view/1490
9. EVALUATING ANTI-MÜLLERIAN HORMONE AND FSH AS PREDICTIVE MARKERS FOR EARLY OVARIAN INSUFFICIENCY (Dadajonova Mashhura Akhmadjon kizi,Mamurova Dilnoza, Trans.). (2025). London International Monthly Conference on Multidisciplinary Research and Innovation (LIMCMRI), 2(1), 860-861. https://worldsiencepub.com/index.php/lmc/article/view/702
10. Komilov, N. (2020). OBIDJON MAHMUDOVACTIVITY IS IN THE SPOTLIGHT OF LOCAL AND FOREIGN SCHOLARS. The Light of Islam, 2020(3), 58-65.
11. Komilov, N. B. (2023). Significance of Jadid Obidjon Mahmudov’s activity as a deputy chairman of the Kokand city Duma and minister of Turkestan’s autonomy. In E3S Web of Conferences (Vol. 402, p. 08018). EDP Sciences.
12. Komilov, N. B. ON THE HISTORIOGRAPHY OF THE FIRST NATIONAL DEMOCRATIC STATE-TURKESTAN'S AUTONOMY. SCIENTIFIC BULLETIN, 39.
13. Komilov, N. B. SOCIO-POLITICAL AND ECONOMIC VIEWS OF JADID OBIDJON MAKHMUDOV. ИЛМИЙ ХАБАРНОМА, 53.
14. Lukmonovich K.B., Islomjonovich K.R. РЕСПИРАТОР ДИСТРЕСС СИНДРОМИДА МУДДАТДАН ОЛДИН ТУҒИЛГАН ЧАҚАЛОҚЛАРДА БУЙРАК УСТИ БЕЗИНИНГ МОРФОЛОГИЯСИ [Electronic resource]. 2025. URL: https://www.tadqiqot.uz/index.php/spjacd/article/view/12877 (accessed: 04.01.2026).
15. Makhmaraimova, S., Khalikova, R., Fayziyeva, K., Jaleel, M. A., Ernazarova, I., Khamrokulova, S., ... & Sapaev, I. Blockchain-Based Wireless Network Security Algorithm for Data Integrity in History Education.
16. Turdimatov D.S., Xolmatov I.X., Xatamov R.I. FARG‘ONA VILOYATIDA 2024 YIL MOBAYNIDA PERINATAL O‘LIMLARNING HOLATI VA ULARNING XUSUSIYATLARI. KPTJ.-2025-N.2.-№2-М
17. Zarnigor, A. (2025). GYNECOLOGICAL AND REPRODUCTIVE HEALTH ISSUES AMONG WOMEN IN ENVIRONMENTALLY VULNERABLE REGIONS OF UZBEKISTAN. SHOKH LIBRARY, 1(12).
