A Study of the Pharmacological Mechanisms and Traditional Modalities in the Treatment of Heart Failure Using Uzbek Herbal Medicine
Keywords:
Ethnopharmacology, Heart Failure, Uzbekistan Flora, Cardiovascular Pharmacology, Medicinal Plants, Bioactive CompoundsAbstract
Ischemic heart disease and subsequent heart failure remain primary global causes of mortality, driving the ongoing search for adjunctive and complementary therapies. The flora of Uzbekistan, situated at the intersection of the Pamir and Tien Shan mountain ranges, harbors over 4,500 species of vascular plants, many of which are integral to Central Asian traditional medicine. This review analyzes recent pharmacological findings on Uzbek ethnobotanicals utilized for cardiovascular conditions. We examine the mechanisms of action, clinical efficacy, safety profiles, and limitations of prominent species, including Leonurus turkestanicus, Matricaria chamomilla, and Atraphaxis pyrifolia. By bridging traditional practices with modern phytochemical profiling, this analysis highlights the therapeutic potential of these indigenous plants while clarifying the rigorous clinical validations still required.
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